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Mechanism: Oxymorphone, the active ingredient in Opana ER, works by binding to opioid receptors in the brain and spinal cord, reducing the perception of pain and potentially causing feelings of euphoria. The extended-release formulation of Opana ER allows for the slow and steady release of oxymorphone, maintaining a consistent level of the medication in the body, which helps to provide prolonged pain relief. 3. Possible Uses and Benefits: Management of moderate to severe chronic pain Long-term pain control for conditions such as cancer pain, severe arthritis, and chronic back pain Improved quality of life by providing consistent and long-lasting pain relief Reduction in the need for multiple daily doses of pain medication 4. Potential Side Effects: Common: Nausea, vomiting, constipation, dizziness, drowsiness, headache, dry mouth, sweating Serious: Respiratory depression, severe allergic reactions, mood changes (e.g., agitation, hallucinations), difficulty urinating, severe stomach/abdominal pain Long-term use can lead to dependence, tolerance, and withdrawal symptoms upon discontinuation 5. Dosage Instructions: Opana ER 15mg is typically taken every 12 hours. The tablet should be swallowed whole with water and not broken, chewed, or crushed, as this can release the drug all at once and increase the risk of side effects and overdose. It is important to follow a healthcare provider’s instructions and not exceed the prescribed dosage. Do not discontinue the medication abruptly without consulting your healthcare provider. 6. Alerts and Precautions: Opana ER can cause drowsiness and dizziness; avoid driving or operating heavy machinery until you know how the medication affects you. Avoid alcohol and other CNS depressants while taking Opana ER, as they can increase the risk of severe side effects. Not recommended for use during pregnancy due to potential harm to the unborn baby. Use with caution in elderly patients, as they may be more sensitive to its effects. Patients with a history of substance abuse should use this medication with caution due to the risk of dependence. Inform your healthcare provider of all medications you are taking to avoid potential interactions. 7. Methods of Consumption: Opana ER 15mg tablets are taken orally, usually every 12 hours. The tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets, as this can release the drug all at once and increase the risk of side effects. 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